Die Forschung mit embryonalen Stammzellen gehört in Deutschland seit Jahren zu den in der Öffentlichkeit besonders kontrovers diskutierten Fragen. Aus ethischer, rechtlicher und sozialwissenschaftlicher Perspektive wirft die Verwendung von humanen embryonalen Stammzellen und induzierten pluripotenten Stammzellen in der Grundlagenforschung, der sich abzeichnenden klinischen Anwendung oder auch der ebenfalls näher rückenden Nutzung von Stammzellen als Testsystemen eine Reihe von Fragen auf, die, neben eher allgemeinen Fragen der Ethik der Stammzellforschung, den Fokus der Beiträge des vorliegenden Sammelbandes bilden.

Das Handbuch führt ein in zentrale Begriffe, Konzeptionen, Themen- und Problemfelder der Tierethik. Neben der Geschichte der Tierethik, relevanten Konzepten und Theorien sowie einer Bandbreite unterschiedlicher Anwendungskontexte findet sich auch eine Darstellung der Tierphilosophie und ihrer wichtigsten Fragestellungen. Das Handbuch will darüber hinaus auch die sich in aktuellen Diskussionen und Kontroversen abzeichnenden Perspektiven der Tierethik umfassend vorstellen. Ziel des Handbuchs ist es, das breite Spektrum inhaltlicher und begrifflicher Aspekte der historischen und gegenwärtigen Tierethik zu reflektieren und einen Einblick in den (...) aktuellen Diskussionsstand zu geben. (shrink)

Der Gegenstand der Medizinethik ist die normative Analyse und ethische Reflexion von praktischen Fragen, denen sich Einzelne oder Gruppen mit Blick auf das Gesundheitswesen und insbesondere mit Blick auf den Umgang mit menschlicher Krankheit und Gesundheit gegenübersehen. Sie gehört damit zu den sogenannten angewandten oder Bereichsethiken.

Name der Zeitschrift: Jahrbuch für Wissenschaft und Ethik Jahrgang: 20 Heft: 1 Seiten: 51-72.

In this paper we seek to clarify the question of what exactly is meant by an “autonomous” decision or act by focusing on the most fundamental personal condition for deciding or acting autonomously. This basic personal requirement has often been overlooked in recent debates; where it has been seen, it is characterized in ways that are too demanding. What is meant here is an individual form of self-relation that seems to be constitutive for leading a life as a human and (...) is likely to be acquired very early in life. This significant personal self-relation has three essential aspects: a primal sense of “self-confidence”, a basic form of “self-assertiveness”, and a fundamental form of “self-esteem”. We will call this the “triple S condition” for autonomy. Our main thesis is that any decision or action which is not based on this triple S condition cannot be called “autonomous”. (shrink)

Founded or unfounded, these objections have not as yet received an adequate answer, i.e., an explanation of the possibility of a philosophy of subjectivity as constituting a reasonable addition to the philosophia perennis, a certain broadening of its perspective, without amounting instead to a simple jettisoning of the thought and gains of centuries. The writings of a Marcel, for example, do not provide such an explanation. Composed wholly within the perspective that is in question, and a little too cavalier in (...) their dismissal of scholastic thought, they cannot really come to grips with that thought, or thereby allay its reasonable suspicions. Even the work of P. de Finance is not wholly satisfactory on this point. As a reviewer of his latest book points out, P. de Finance makes constant and brilliant use of insights gained from the perspective of subjectivity, but he skirts around, without ever really meeting head on, the problems it raises. (shrink)

The difficulty with this point of view and the reason why I characterize it as false do not spring from the mere fact that thought is abstract while experience is concrete. For, on the one hand, the abstract character of thought need not be interpreted negatively, as leaving out the rich variety and profusion of the concrete world in favor of some bare common denominator. Concreteness itself can be seen as a limitation which thought overcomes.ion then becomes an enriching process, (...) a process by which the mind, out of its own superior abundance, illumines and completes the data presented to it, so that from the welter and confusion of particular instances it is able to grasp the universal and valid-for-all, and from the fugitive contingency of the concrete to redeem the abidingly true. In this light, abstractiveness is not a vice but a virtue of thought and, far from weakening the intellectualist position, serves rather to reinforce it. (shrink)

Jointly coordinated affective activities are fundamental for social relationships. This study investigates a naturally occurring interaction between two women who produced reciprocal emotional stances towards similar past experiences. Adopting a microanalytic approach, we describe how the participants re-enact their past experiences through different but aligning synchronized gestures. This embodied dialogue evolves into affective flooding, in which participants co-produce their body memories of pulling down window blinds to block out sunshine. We show how the participants live this moment intercorporeally and how (...) multiple timescales are tied together in gesture, which is both an incarnation of body history and a novel expression of it. Thus, collaborative gesturing is a resource for experiencing together emotions re-enacted from body memories. Contributing to our understanding of the intercorporeality of human action, we provide an empirical investigation into how emotions and multiple timescales are nested in cooperative gestures. Data are in Finnish with English translations. (shrink)

Based on the reconstruction of the development of 14 food supply chain initiatives in 7 European countries, we developed a conceptual framework that demonstrates that the process of increasing the sustainability of food supply chains is rooted in strategic choices regarding governance , embedding, and marketing and in the coordination of these three dimensions that are inextricably interrelated. The framework also shows that when seeking to further develop an initiative (e.g., through scaling up or product diversification) these interrelations need continuous (...) rebalancing. We argue that the framework can serve different purposes: it can be used as an analytical tool by researchers studying food supply chain dynamics, as a policy tool by policymakers that want to support the development of sustainable food supply chains, and as a reflexive tool by practitioners and their advisors to help them to position themselves, develop a clear strategy, find the right allies, develop their skills, and build the capacities that they need. In this paper, we elaborate upon the latter function of the framework and illustrate this briefly with empirical evidence from three of the initiatives that we studied. (shrink)

The current German criticism of HUGO centers around the term ‘human dignity’; consenquentialist and autonomy-based arguments are used. The debate culminates in questioning the integrity of bioethics as a scholarly discipline and has created a heterogeneous coalition of disparate political and social groups that oppose any research that would facilitate genetic pre-selection of human characteristics.

Society’s relationship with modern animal farming is an ambivalent one: on the one hand there is rising criticism about modern animal farming; on the other hand people appreciate certain aspects of it, such as increased food safety and low food prices. This ambivalence reflects the two faces of modernity: the negative (exploitation of nature and loss of traditions) and the positive (progress, convenience, and efficiency). This article draws on a national survey carried out in the Netherlands that aimed at gaining (...) a deeper understanding about the acceptance of modern dairy farming in Dutch society. People take two dimensions into account when evaluating different aspects of modern dairy farming: (1) the way living beings are used for production and (2) the way a dairy farm functions as a business. In both these dimensions people appeared to adopt cautious opinions: most people preferred relatively traditional and natural farms and were concerned about the use of nature and treatment of animals in modern production—although this did not imply an outright rejection of modern animal farming. The study also looked for (and sought to explain) differences of opinion between social groups. Besides socio-demographic factors such as age and gender, farming experience and value-orientation (such as socially minded and professional) appeared to be important variables. The values and convictions within modern society can help to explain why some people are greatly concerned about animal welfare while some show less concern. This diversity also helps to explain why general information campaigns are quite ineffective in allaying concerns about modern animal farming. (shrink)

The elaboration of a complete and original system of philosophy in any age demands an intellect of great scope and power. In an age like our own, which has become increasingly hostile to systematic thought, it demands a good deal of courage as well. The Modes of Being of Mr. Weiss proves that he possesses both to a high degree.

Society’s relationship with modern animal farming is an ambivalent one: on the one hand there is rising criticism about modern animal farming; on the other hand people appreciate certain aspects of it, such as increased food safety and low food prices. This ambivalence reflects the two faces of modernity: the negative (exploitation of nature and loss of traditions) and the positive (progress, convenience, and efficiency). This article draws on a national survey carried out in the Netherlands that aimed at gaining (...) a deeper understanding about the acceptance of modern dairy farming in Dutch society. People take two dimensions into account when evaluating different aspects of modern dairy farming: (1) the way living beings are used for production and (2) the way a dairy farm functions as a business. In both these dimensions people appeared to adopt cautious opinions: most people preferred relatively traditional and natural farms and were concerned about the use of nature and treatment of animals in modern production—although this did not imply an outright rejection of modern animal farming. The study also looked for (and sought to explain) differences of opinion between social groups. Besides socio-demographic factors such as age and gender, farming experience and value-orientation (such as socially minded and professional) appeared to be important variables. The values and convictions within modern society can help to explain why some people are greatly concerned about animal welfare while some show less concern. This diversity also helps to explain why general information campaigns are quite ineffective in allaying concerns about modern animal farming. (shrink)

The rapidly changing field of genetics affects society through advances in health-care and through implications of genetic research. This study addresses the impacts of new genetic discoveries and technologies on different segments of today's society. The book begins with a chapter on genetic complexity, and subsequent chapters discuss moral and ethical questions arising from today's genetics from the perspectives of health care professionals, the media, the general public, special interest groups and commercial interests.

Der Begriff ›Tierversuch‹ kann in einem engen und in einem weiten Sinne verwendet werden. Im weiten Sinne kann man unter ›Tierversuch‹ jede wissenschaftliche oder experimentelle Verwendung von Tieren verstehen. Im engeren Sinn, der auch dem Tierversuchsrecht der Europäischen Union oder dem deutschen Tierschutz-Gesetz zugrunde liegt, bezeichnet der Begriff ›Tierversuch‹ solche wissenschaftlichen Verfahren mit lebenden Tieren, die mit Schmerzen, Belastungen oder Schäden der Tiere verbunden sein können. Artikel 3 der einschlägigen Richtlinie 2010/63/EU beispielsweise definiert den Tierversuch als »jede invasive oder nicht (...) invasive Verwendung eines Tieres zu Versuchszwecken oder anderen wissenschaftlichen Zwecken mit bekanntem oder unbekanntem Ausgang, oder zu Ausbildungszwecken, die bei dem Tier Schmerzen, Leiden, Ängste oder dauerhafte Schäden in einem Ausmaß verursachen kann, das dem eines Kanüleneinstichs gemäß guter tierärztlicher Praxis gleichkommt oder darüber hinaus geht«. Der Geltungsbereich der Richtlinie umfasst neben lebenden, nichtmenschlichen Wirbeltieren auch selbständig Nahrung aufnehmende Larven, Säugetierföten ab dem letzten Drittel ihrer normalen Entwicklung und lebende Kopffüßer. Ähnliche Bestimmungen finden sich auch im deutschen Tierschutz-Gesetz. (shrink)

Philosophie nach Georg Meggle zeichnet sich aus durch kommunikative Offenheit, durch begriffliche Unbestechlichkeit und durch ihr Engagement in der Welt. Die Beiträge in diesem Band orientieren sich an diesem Philosophieverständnis und sind aus Anlass eines Symposiums zu Ehren von Georg Meggle als Originalbeiträge geschrieben worden. Der Band verbindet die theoretischen und praktischen Aspekte der analytischen Philosophie: So sind die Essays zur Hälfte der theoretischen, meist sprach-analytischen, zur Hälfte der praktischen, meist praktisch-politischen Philosophie zuzuordnen. Die Texte vereint das Ideal des Strebens (...) nach begrifflicher Klarheit und welthaltiger Relevanz, nach Dialog. Sie beschreiten neue Wege der analytischen Philosophie und weisen somit den Weg in die Zukunft der Philosophie als gesellschaftlich relevanter Disziplin. Mit Beiträgen u.a. von: Franz von Kutschera, Peter Singer, Wolfgang Lenzen, Wolfgang Spohn, Reinhard Merkel, Rainer Hegselmann, Peter Rohs und Georg Meggle. (shrink)

BackgroundTo probe the functional role of brain oscillations, transcranial alternating current stimulation has proven to be a useful neuroscientific tool. Because of the excessive tACS-caused artifact at the stimulation frequency in electroencephalography signals, tACS + EEG studies have been mostly limited to compare brain activity between recordings before and after concurrent tACS. Critically, attempts to suppress the artifact in the data cannot assure that the entire artifact is removed while brain activity is preserved. The current study aims to evaluate the (...) feasibility of specific artifact correction techniques to clean tACS-contaminated EEG data.New MethodIn the first experiment, we used a phantom head to have full control over the signal to be analyzed. Driving pre-recorded human brain-oscillation signals through a dipolar current source within the phantom, we simultaneously applied tACS and compared the performance of different artifact-correction techniques: sine subtraction, template subtraction, and signal-space projection. In the second experiment, we combined tACS and EEG on one human subject to demonstrate the best-performing data-correction approach in a proof of principle.ResultsThe tACS artifact was highly attenuated by SSP in the phantom and the human EEG; thus, we were able to recover the amplitude and phase of the oscillatory activity. In the human experiment, event-related desynchronization could be restored after correcting the artifact.Comparison With Existing MethodsThe best results were achieved with SSP, which outperformed sine subtraction and template subtraction.ConclusionOur results demonstrate the feasibility of SSP by applying it to a phantom measurement with pre-recorded signal and one human tACS + EEG dataset. For a full validation of SSP, more data are needed. (shrink)

This paper presents Cusanus’ dialogue of 1462, named after and centred on the concept of non-aliud, and exploits its speculative resources for conceiving the relationship between God and the realm of finite entities. Furthermore, it points to the elements of self-constitution of the absolute and of the latter’s grounding relation towards the contingent. Finally, it is argued that Cusanus’ concept of non-aliud offers a valuable contribution to the present debate about an adequate concept of God.

In paediatric oncology, research and treatments are often closely combined, which may compromise voluntary informed consent of parents. We identified two key scenarios in which voluntary informed consent for paediatric oncology studies is potentially compromised due to the intertwinement of research and care. The first scenario is inclusion by the treating paediatric oncologist, the second scenario concerns treatments confined to the research context. In this article we examine whether voluntary informed consent of parents for research is compromised in these two (...) scenarios, and if so whether this is also morally problematic. For this, we employ the account of voluntary consent from Nelson and colleagues, who assert that voluntary consent requires substantial freedom from controlling influences. We argue that, in the absence of persuasion or manipulation, inclusion by the treating physician does not compromise voluntariness. However, it may function as a risk factor for controlling influence as it narrows the scope within which parents make decisions. Furthermore, physician appeal to reciprocity is not controlling as it constitutes persuasion. In addition, framing information is a form of informational manipulation and constitutes a controlling influence. In the second scenario, treatments confined to the research context qualify as controlling if the available options are restricted through manipulation of options. Although none of the influences is morally problematic in itself, a combination of influences may create morally problematic instances of involuntary informed consent. Therefore, safeguards should be implemented to establish an optimal environment for parents to provide voluntary informed consent in an integrated research-care context. (shrink)